Which condition is associated with a significantly enlarged liver?

The condition associated with a significantly enlarged liver is hepatomegaly. Hepatomegaly refers specifically to the enlargement of the liver beyond its normal size, which can be indicative of various underlying health issues, such as infections, liver diseases like hepatitis, fatty liver disease, or other systemic conditions that affect liver function.

Understanding hepatomegaly is essential for diagnosing and managing liver-related conditions, as it serves as a clinical sign that warrants further investigation to determine the underlying cause of the enlargement. In contrast, the other conditions listed do not directly relate to liver enlargement; instead, they pertain to different bodily systems and issues.